Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | STK4 | Q13043 | 1/20 | 0.41 |
| ▸ | STK3 | Q13188 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101818 | 0.90 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AMTOR | |
| SCHEMBL4722479 | 0.87 | MTOR (0.45) | MEN1KMT2ANPC1RAB9AMTOR | |
| SCHEMBL4721933 | 0.85 | MTOR (0.45) | MEN1KMT2ANPC1RAB9AMTOR | |
| SCHEMBL4720924 | 0.85 | DGAT1 (0.48) | MEN1KMT2AMTORSMG1CCNT1 | |
| SCHEMBL4722075 | 0.73 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL14101741 | 0.73 | MEN1 (0.46) | MEN1KMT2ASTK4STK3LRRK2 | |
| SCHEMBL4722685 | 0.73 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9ACCNT1 | |
| SCHEMBL4719536 | 0.72 | MAPT (0.51) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4724315 | 0.72 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9ASTK4 | |
| SCHEMBL4719650 | 0.72 | PRKDC (0.48) | MEN1KMT2ANPC1RAB9ASTK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |