Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | STK4 | Q13043 | 1/20 | 0.42 |
| ▸ | STK3 | Q13188 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721877 | 0.87 | MEN1 (0.47) | MTORSMG1MEN1KMT2ASTK4 | |
| SCHEMBL4721933 | 0.86 | MTOR (0.45) | MTORSMG1MEN1KMT2ASTK4 | |
| SCHEMBL14101818 | 0.84 | MEN1 (0.46) | MTORSMG1MEN1KMT2ASTK4 | |
| SCHEMBL4722243 | 0.82 | MAPT (0.49) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4720924 | 0.80 | DGAT1 (0.48) | MTORSMG1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4719650 | 0.76 | PRKDC (0.48) | MEN1KMT2ASTK4STK3LRRK2 | |
| SCHEMBL14101741 | 0.74 | MEN1 (0.46) | MEN1KMT2ASTK4STK3LRRK2 | |
| SCHEMBL4719536 | 0.73 | MAPT (0.51) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| SCHEMBL4724315 | 0.73 | MEN1 (0.45) | MEN1KMT2ASTK4STK3LRRK2 | |
| SCHEMBL4723995 | 0.72 | GAA (0.50) | MEN1KMT2ASTK4STK3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |