Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102092 | 0.89 | PDK2 (0.34) | NOTUMMAPTHSD17B10S1PR1 | |
| SCHEMBL4722070 | 0.88 | P2RX7 (0.39) | F2F10NOTUMP2RX7S1PR1 | |
| SCHEMBL4722067 | 0.88 | P2RX7 (0.39) | F2F10NOTUMP2RX7S1PR1 | |
| SCHEMBL4721608 | 0.85 | AKR1B10 (0.33) | AKR1B10AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL14101834 | 0.85 | F2 (0.36) | F2F10ARNOTUMTUBB4A | |
| SCHEMBL4720700 | 0.84 | ITGB2 (0.39) | — | |
| SCHEMBL4720703 | 0.84 | ITGB2 (0.39) | — | |
| SCHEMBL14101952 | 0.84 | AKR1B10 (0.32) | AKR1B10AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL4724969 | 0.82 | NOTUM (0.36) | NOTUMMAPTHSD17B10ALOX15S1PR1 | |
| SCHEMBL4722462 | 0.82 | NOTUM (0.36) | NOTUMMAPTHSD17B10ALOX15S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |