Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722241 | 1.00 | ACACB (0.36) | ACACBP2RX7UGCGNOTUMF10 | |
| SCHEMBL14101837 | 0.88 | F10 (0.40) | UGCGF10F2 | |
| SCHEMBL4720966 | 0.81 | EGFR (0.35) | UGCG | |
| SCHEMBL4722070 | 0.80 | P2RX7 (0.39) | P2RX7NOTUMF10F2 | |
| SCHEMBL4722067 | 0.80 | P2RX7 (0.39) | P2RX7NOTUMF10F2 | |
| SCHEMBL4720518 | 0.79 | ITGB2 (0.35) | ACACBP2RX7NOTUMF10F2 | |
| SCHEMBL4720758 | 0.79 | CDK1 (0.35) | ACACBP2RX7NOTUMF10F2 | |
| SCHEMBL4720760 | 0.79 | CDK1 (0.35) | ACACBP2RX7NOTUMF10F2 | |
| SCHEMBL4720516 | 0.79 | ITGB2 (0.35) | ACACBP2RX7NOTUMF10F2 | |
| SCHEMBL4721351 | 0.79 | P2RX7 (0.34) | ACACBP2RX7NOTUMF10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |