Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | CALCA | P06881 | 10/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314682 | 0.91 | OPRK1 (0.42) | DPP8CHRM1L3MBTL3L3MBTL1OPRK1 | |
| SCHEMBL3279496 | 0.90 | DPP8 (0.49) | DPP8CHRM1ALOX15CYP2D6CYP2C19 | |
| SCHEMBL4722468 | 0.88 | AKT1 (0.43) | CHRM1L3MBTL3L3MBTL1OPRK1 | |
| SCHEMBL3314171 | 0.87 | DPP8 (0.47) | DPP8CHRM1ALOX15CALCAL3MBTL3 | |
| SCHEMBL4717751 | 0.85 | MC4R (0.43) | CALCAOPRK1 | |
| SCHEMBL4720817 | 0.83 | DPP8 (0.43) | DPP8CHRM1ALOX15CYP3A4CALCA | |
| SCHEMBL3279033 | 0.83 | DPP8 (0.48) | DPP8CHRM1ALOX15CYP2D6CYP2C19 | |
| SCHEMBL29496558 | 0.81 | CHRM1 (0.56) | DPP8CHRM1ALOX15L3MBTL3L3MBTL1 | |
| SCHEMBL3285190 | 0.81 | OPRK1 (0.44) | DPP8CHRM1L3MBTL3L3MBTL1OPRK1 | |
| SCHEMBL7012362 | 0.79 | DPP8 (0.47) | DPP8CHRM1ALOX15CYP3A4CALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | claimed |