Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719884 | 0.87 | L3MBTL1 (0.36) | NPSR1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4721927 | 0.87 | ALOX5 (0.37) | NPSR1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4719229 | 0.85 | IMPDH2 (0.40) | NPSR1MAPTNPC1RAB9ALMNA | |
| SCHEMBL4723560 | 0.83 | MAPT (0.39) | NPSR1MAPTMEN1KMT2AGAA | |
| SCHEMBL4722439 | 0.78 | MEN1 (0.43) | NPSR1MAPTMEN1KMT2AGAA | |
| SCHEMBL4721167 | 0.78 | NPSR1 (0.43) | NPSR1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4719649 | 0.78 | MEN1 (0.40) | NPSR1MAPTMEN1KMT2AGAA | |
| SCHEMBL4719701 | 0.78 | GAA (0.41) | NPSR1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4722197 | 0.78 | MEN1 (0.32) | MEN1KMT2AGAA | |
| SCHEMBL4719136 | 0.78 | MAPT (0.37) | NPSR1MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |