SCHEMBL472259

SCHEMBL472259

C=C(C)C(=O)NC(C)(C)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
CYP2C19 P33261 3/20 0.38
HIF1A Q16665 2/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
TGFBR1 P36897 1/20 0.37
KDM4E B2RXH2 2/20 0.34
FFAR1 O14842 1/20 0.34
CPT2 P23786 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 4/20 0.32
TET2 Q6N021 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
NAALAD2 Q9Y3Q0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730664 0.85 TGFBR1 (0.34) TGFBR1ALDH1A1
SCHEMBL1827439 0.82 HMGCR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL1828957 0.82 HMGCR (0.38) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL7860191 0.80 CA4 (0.34) TGFBR1
SCHEMBL5052589 0.80 NAALAD2 (0.44) HIF1ATSHRTGFBR1KDM4EALDH1A1
SCHEMBL1825121 0.80 HMGCR (0.37) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL1826177 0.80 HSD17B10 (0.34) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL9805999 0.78 EPHX1 (0.40) TGFBR1KDM4ETDP1ALDH1A1
SCHEMBL21612680 0.78 TGFBR1 (0.35) TGFBR1KDM4ETDP1ALDH1A1
SCHEMBL7611640 0.78 TGFBR1 (0.39) TGFBR1KDM4ETDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
US-11999908-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-06-04 US claimed
EP-4369081-A2 METHOD FOR PRODUCING AN OPHTHALMIC PRODUCT Alcon Inc. (CH) 2024-05-15 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
US-11867874-B2 Insert materials with high oxygen permeability and high refractive index ALCON INC. (CH) 2024-01-09 US claimed
WO-2023228055-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 WO claimed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 US claimed
US-20030234103-A1 Method for treating subterranean formation SCHLUMBERGER TECHNOLOGY CORPORATION 2003-12-25 US claimed
US-6610310-B2 Immunology response; side effect reduction AMERICAN CYANAMID COMPANY 2003-08-26 US claimed
US-20030021793-A1 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION ZOETIS SERVICES LLC 2003-01-30 US claimed
CN-1087177-C immunologic adjuvant DIMINAK CO LTD (CH) 2002-07-10 CN claimed
EP-0934077-A2 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION DIMMINACO AG/SA/LTD. (CH) 1999-08-11 EP claimed
WO-1998017310-A2 POLYANIONIC POLYMERS AS ADJUVANTS FOR MUCOSAL IMMUNIZATION DIMMINACO AG/S.A./LTD. (CH) 1998-04-30 WO claimed
CN-1171053-A Vaccine adjuvants DIMINAK CO LTD (CH) 1998-01-21 CN claimed
US-4649183-A POLYMER OF ACRYLAMIDE AND ACRYLAMIDOALKANOIC ACID OR SALT, FLOW CONTROL AGNETS, ENHANCED OIL RECOVERY UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 1987-03-10 US claimed
EP-0206489-A2 Calcium-Tolerant N-Substituted Acrylamides as Thickeners for aqueous Systems UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 1986-12-30 EP claimed
US-4584358-A ENHANCED OIL RECOVERY UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 1986-04-22 US claimed