Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730664 | 0.82 | TGFBR1 (0.34) | TGFBR1 | |
| SCHEMBL472259 | 0.80 | HMGCR (0.39) | TGFBR1 | |
| SCHEMBL9805999 | 0.75 | EPHX1 (0.40) | TGFBR1 | |
| SCHEMBL21612680 | 0.75 | TGFBR1 (0.35) | TGFBR1 | |
| SCHEMBL7611640 | 0.75 | TGFBR1 (0.39) | TGFBR1 | |
| SCHEMBL719408 | 0.74 | ALDH1A1 (0.49) | CA4 | |
| SCHEMBL3662136 | 0.74 | POLB (0.44) | TGFBR1 | |
| SCHEMBL491400 | 0.74 | TDP1 (0.35) | TGFBR1 | |
| SCHEMBL147076 | 0.74 | POLB (0.43) | TGFBR1 | |
| SCHEMBL6232119 | 0.72 | ALDH1A1 (0.52) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868412-B1 | COMPOSITION FOR PRODUCING LIGHT PLASTER AND ITS USE | HENKEL KGAA (DE) | 2001-09-05 | — | — | EP | disclosed |
| US-6162839-A | Composition for producing light plaster, production of the foaming agent used therefor and its use | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-12-19 | — | — | US | disclosed |
| EP-0868412-A1 | COMPOSITION FOR PRODUCING LIGHT PLASTER, PRODUCTION OF THE FOAMING AGENT USED THEREFOR AND ITS USE | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-07 | — | — | EP | disclosed |
| WO-1997022567-A1 | COMPOSITION FOR PRODUCING LIGHT PLASTER, PRODUCTION OF THE FOAMING AGENT USED THEREFOR AND ITS USE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-06-26 | — | — | WO | disclosed |