SCHEMBL472264

SCHEMBL472264

C=C(C)C(=O)NC(C)CCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.46
ALDH1A1 P00352 4/20 0.42
HPGD P15428 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
THRB P10828 1/20 0.36
HCAR3 P49019 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
HDAC7 Q8WUI4 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27597202 0.88 TAS1R3 (0.45) TGFBR1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL472265 0.85 ADH1B (0.46) TGFBR1KMT2ATAS1R3TAS1R1MEN1
SCHEMBL11747509 0.85 ADH1B (0.46) TGFBR1KMT2ATAS1R3TAS1R1MEN1
SCHEMBL14219281 0.85 ADH1B (0.46) TGFBR1KMT2ATAS1R3TAS1R1MEN1
SCHEMBL11675845 0.85 ADH1B (0.46) TGFBR1KMT2ATAS1R3TAS1R1MEN1
SCHEMBL29519156 0.83 TGFBR1 (0.50) TGFBR1ALDH1A1NPC1RAB9ACYP2C9
SCHEMBL554944 0.83 TGFBR1 (0.48) TGFBR1ALDH1A1HPGDPOLBKMT2A
SCHEMBL11009489 0.82 TGFBR1 (0.44) TGFBR1ALDH1A1NPC1RAB9ACYP2C9
Propane SCHEMBL28191962 0.81 TGFBR1 (0.41) TGFBR1CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL1826412 0.81 TGFBR1 (0.47) TGFBR1ALDH1A1TAS1R3TAS1R1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO claimed
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO disclosed
EP-3284599-B1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORP (JP) 2019-07-03 EP disclosed
EP-2412739-A1 Radiation curable aqueous compositions Cytec Surface Specialties, S.A. (BE) 2012-02-01 EP disclosed
US-7759426-B2 Polyaniline-containing composition and process for its production NIPPON SHOKUBAI CO., LTD. (JP) 2010-07-20 US disclosed
US-20080194763-A1 Polyaniline-Containing Composition and Process for its Production NIPPON SHOKUBAI CO., LTD. (JP) 2008-08-14 US disclosed
EP-1854844-A1 POLYANILINE-CONTAINING COMPOSITION AND PROCESS FOR PRODUCTION OF THE SAME Nippon Shokubai Co., Ltd. (JP) 2007-11-14 EP disclosed