SCHEMBL10102735

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14088989	0.89	NR1H4 (0.81)	NR1H4RAB9ANPC1SMN1; SMN2MAPK1
	SCHEMBL1468045	0.85	NR1H4 (0.58)	NR1H4MAPTALDH1A1RAB9AMCL1
	SCHEMBL472311	0.84	ALDH1A1 (0.61)	NR1H4MAPTALDH1A1RAB9AMCL1
	SCHEMBL28134761	0.83	NR1H4 (0.73)	NR1H4KDM4ETRPV1HSD17B10HDAC1
	SCHEMBL10102714	0.83	NR1H4 (0.72)	NR1H4RAB9ANPC1SMN1; SMN2MAPK1
	SCHEMBL2061403	0.82	NR1H4 (0.71)	NR1H4SMN1; SMN2MAPK1KDM4ETRPV1
	SCHEMBL13814817	0.82	NR1H4 (0.71)	NR1H4MAPTNPC1KDM4ETRPV1
	SCHEMBL1468708	0.82	ALDH1A1 (0.53)	NR1H4MAPTALDH1A1RAB9AMCL1
	SCHEMBL27193216	0.82	HDAC1 (0.71)	MAPTALDH1A1RAB9AMCL1NPC1
	SCHEMBL12528011	0.80	RAB9A (0.64)	MAPTALDH1A1RAB9AMCL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.