Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 14/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4718934 | 0.93 | NOTUM (0.47) | NOTUMUGCGS1PR1PDE4APDE4B | |
| SCHEMBL4722706 | 0.93 | NOTUM (0.48) | NOTUMUGCGS1PR1PDE4APDE4B | |
| SCHEMBL4722787 | 0.93 | NOTUM (0.48) | NOTUMUGCGS1PR1PDE4APDE4B | |
| SCHEMBL4722716 | 0.92 | NOTUM (0.38) | HSD11B1NOTUMUGCGS1PR1PDE4A | |
| SCHEMBL4719376 | 0.92 | NOTUM (0.49) | NOTUMUGCGS1PR1PDE4APDE4B | |
| SCHEMBL4721983 | 0.91 | NOTUM (0.40) | NOTUMUGCGS1PR1 | |
| SCHEMBL4721118 | 0.91 | NOTUM (0.43) | NOTUM | |
| SCHEMBL4721985 | 0.89 | NOTUM (0.46) | NOTUM | |
| SCHEMBL4724695 | 0.89 | P2RX7 (0.38) | HSD11B1UGCGPDE4APDE4BPDE4C | |
| SCHEMBL4719498 | 0.89 | P2RX7 (0.38) | HSD11B1UGCGPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |