Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721118 | 0.94 | NOTUM (0.43) | NOTUMEPHX2CHRM4DGAT2MAPT | |
| SCHEMBL4722787 | 0.91 | NOTUM (0.48) | NOTUMEPHX2MAPT | |
| SCHEMBL4722706 | 0.91 | NOTUM (0.48) | NOTUMEPHX2MAPT | |
| SCHEMBL4721983 | 0.90 | NOTUM (0.40) | NOTUMMAPT | |
| SCHEMBL4723394 | 0.89 | HSD11B1 (0.39) | NOTUM | |
| SCHEMBL4718934 | 0.89 | NOTUM (0.47) | NOTUM | |
| SCHEMBL4722716 | 0.88 | NOTUM (0.38) | NOTUM | |
| SCHEMBL4719376 | 0.87 | NOTUM (0.49) | NOTUM | |
| SCHEMBL14101717 | 0.86 | PDE4A (0.35) | NOTUMMAPT | |
| SCHEMBL4722947 | 0.86 | MAPT (0.39) | NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |