Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646805 | 0.84 | ALDH1A1 (0.51) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL20741944 | 0.79 | GAA (0.41) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL25201648 | 0.77 | MAOB (0.45) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL8806810 | 0.72 | THRB (0.58) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL14101965 | 0.71 | GAA (0.41) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL28598401 | 0.71 | GAA (0.65) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL27940470 | 0.70 | DHODH (0.44) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL31310458 | 0.70 | THRB (0.42) | DHODHTHRBTHRAGAAMAPT | |
| SCHEMBL5396333 | 0.70 | RXRB (0.41) | DHODHSMN1; SMN2 | |
| SCHEMBL25430974 | 0.69 | THRB (0.48) | DHODHTHRBTHRAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |