Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722208 | 0.96 | MAPT (0.47) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4723534 | 0.90 | MAPT (0.39) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL14102014 | 0.89 | MAPT (0.38) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4722264 | 0.86 | MAPT (0.47) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4724440 | 0.85 | MAPT (0.38) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4721273 | 0.84 | MAPT (0.37) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4720715 | 0.81 | MAPT (0.46) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4720458 | 0.79 | MAPT (0.36) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4719402 | 0.79 | MAPT (0.44) | MAPTALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL4722686 | 0.78 | NPSR1 (0.65) | MAPTALDH1A1LMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |