Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102014 | 0.95 | MAPT (0.38) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4724440 | 0.92 | MAPT (0.38) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4722208 | 0.88 | MAPT (0.47) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4723534 | 0.88 | MAPT (0.39) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4723852 | 0.84 | MAPT (0.48) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4722053 | 0.84 | CTDSP1 (0.36) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4720984 | 0.81 | ALDH1A1 (0.36) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4721931 | 0.79 | MAPT (0.36) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL4722543 | 0.78 | MEN1 (0.43) | MAPTALDH1A1LMNAKMT2AGAA | |
| SCHEMBL4719649 | 0.77 | MEN1 (0.40) | MAPTALDH1A1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |