Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720984 | 0.95 | ALDH1A1 (0.36) | MAPTP2RY1ALDH1A1GAAKDM4E | |
| SCHEMBL4721931 | 0.91 | MAPT (0.36) | MAPTALDH1A1GAAHTTNPSR1 | |
| SCHEMBL14101727 | 0.89 | MAPT (0.36) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4722264 | 0.89 | MAPT (0.47) | MAPTALDH1A1GAACYP2C9HTT | |
| SCHEMBL4721816 | 0.86 | MAPT (0.38) | MAPTP2RY1ALDH1A1CYP2C9NPSR1 | |
| SCHEMBL4722053 | 0.86 | CTDSP1 (0.36) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4723534 | 0.85 | MAPT (0.39) | MAPTP2RY1ALDH1A1GAAKDM4E | |
| SCHEMBL4720374 | 0.85 | PSMB5 (0.35) | MAPTALDH1A1GAAKDM4ECYP1A2 | |
| SCHEMBL4722028 | 0.84 | MAPT (0.39) | MAPTP2RY1ALDH1A1CYP2C9HTT | |
| SCHEMBL4720715 | 0.84 | MAPT (0.46) | MAPTALDH1A1GAACYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |