Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724440 | 0.95 | MAPT (0.38) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL14102014 | 0.93 | MAPT (0.38) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4723852 | 0.90 | MAPT (0.48) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4721273 | 0.88 | MAPT (0.37) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4720458 | 0.85 | MAPT (0.36) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4722208 | 0.85 | MAPT (0.47) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4722543 | 0.82 | MEN1 (0.43) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4720984 | 0.81 | ALDH1A1 (0.36) | MAPTALDH1A1GAAKDM4EHTT | |
| SCHEMBL4721931 | 0.79 | MAPT (0.36) | MAPTALDH1A1GAAHTTLMNA | |
| SCHEMBL14101727 | 0.78 | MAPT (0.36) | MAPTALDH1A1LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |