Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.34 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724105 | 0.86 | TLR7 (0.44) | TLR7ALDH1A1SMN1; SMN2PARP14MAPT | |
| SCHEMBL4767581 | 0.85 | SLC2A1 (0.35) | TLR7SLC2A1SLC2A2SLC2A3PIM1 | |
| SCHEMBL5504922 | 0.79 | CNR1 (0.34) | SLC2A1SLC2A2SLC2A3PIM1CSNK2B | |
| SCHEMBL4766269 | 0.77 | PARP14 (0.33) | TLR7SLC2A1SLC2A2SLC2A3PIM1 | |
| SCHEMBL5507582 | 0.77 | PTGES (0.32) | PIM1CSNK2BCSNK2A2PIM3PIM2 | |
| SCHEMBL4764975 | 0.73 | PTGES (0.33) | SLC2A1SLC2A2SLC2A3CSNK2BCSNK2A2 | |
| SCHEMBL5271211 | 0.70 | IDO1 (0.37) | TLR7ALDH1A1PARP14MAPT | |
| SCHEMBL4766121 | 0.70 | KMT2A (0.42) | ALDH1A1PARP14MAPT | |
| SCHEMBL4063897 | 0.69 | ALOX5 (0.34) | ALDH1A1MAPTATM | |
| SCHEMBL4767545 | 0.68 | PARP14 (0.35) | TLR7ALDH1A1PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968587-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | Coley Pharmaceutical, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007075468-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-05 | — | — | WO | disclosed |