Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 6/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766269 | 0.85 | PARP14 (0.33) | PTGESPARP14PIM1CSNK2A2CSNK2B | |
| SCHEMBL4764975 | 0.85 | PTGES (0.33) | PTGESPARP14CSNK2A2CSNK2BCNR1 | |
| SCHEMBL5271211 | 0.85 | IDO1 (0.37) | PARP14 | |
| SCHEMBL5504922 | 0.83 | CNR1 (0.34) | PARP14PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL4767581 | 0.77 | SLC2A1 (0.35) | PARP14PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL4724437 | 0.77 | TLR7 (0.34) | PARP14PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL4766121 | 0.73 | KMT2A (0.42) | PARP14 | |
| SCHEMBL4767545 | 0.71 | PARP14 (0.35) | PARP14 | |
| SCHEMBL4724105 | 0.70 | TLR7 (0.44) | PARP14 | |
| SCHEMBL5276474 | 0.67 | DCPS (0.40) | PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851218-A2 | HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINE COMPOUNDS AND METHODS | 3M Innovative Properties Company (US) | 2007-11-07 | — | — | EP | disclosed |
| EP-1850849-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | Coley Pharmaceutical Group, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006091647-A2 | METHOD OF PREFERENTIALLY INDUCING THE BIOSYNTHESIS OF INTERFERON | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006091567-A2 | HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINE COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-08-31 | — | — | WO | disclosed |