SCHEMBL472453

SCHEMBL472453

C=CCc1c(O)cccc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.41
GABRB2 P47870 3/20 0.41
SRD5A1 P18405 1/20 0.40
XDH P47989 1/20 0.38
KMT2A Q03164 7/20 0.37
MAPT P10636 6/20 0.37
MEN1 O00255 6/20 0.37
MAPK1 P28482 2/20 0.37
KDM4E B2RXH2 4/20 0.37
GAA P10253 3/20 0.37
AKR1B1 P15121 2/20 0.37
ALDH1A1 P00352 2/20 0.37
ALDH2 P05091 1/20 0.37
HPGD P15428 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69556 0.85 GABRA1 (0.48) GABRA1GABRB2SRD5A1XDHKMT2A
SCHEMBL3712558 0.80 MAOB (0.38) KMT2AMEN1KDM4EGAAALDH1A1
SCHEMBL10587406 0.79 GABRA1 (0.53) GABRA1GABRB2SRD5A1XDHKMT2A
SCHEMBL6690960 0.79 GABRA1 (0.44) GABRA1GABRB2SRD5A1XDHKMT2A
SCHEMBL254084 0.78 GABRA1 (0.57) GABRA1GABRB2SRD5A1XDHKMT2A
SCHEMBL9620573 0.78 GABRA1 (0.42) GABRA1GABRB2SRD5A1XDHKMT2A
SCHEMBL4931545 0.78 GABRA1 (0.42) GABRA1GABRB2SRD5A1XDHKMT2A
SCHEMBL9272904 0.76 GABRA1 (0.41) GABRA1GABRB2SRD5A1XDHKMT2A
SCHEMBL9280552 0.76 IMPDH2 (0.40) GABRA1GABRB2KMT2AMAPTMEN1
SCHEMBL4926856 0.76 GABRA1 (0.41) GABRA1GABRB2SRD5A1XDHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096751-A1 MACROCYCLIC INHIBITORS OF ATP CITRATE LYASE ESPERION THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed
CN-113227290-B Silane compound and composition thereof 引能仕株式会社 2024-05-03 CN disclosed
US-11746226-B2 Polymer composition, foam and method thereof TSRC CORPORATION (TW) 2023-09-05 US disclosed
CN-111333795-B Hydrogenated block copolymer, resin composition, and article obtained using same 株式会社可乐丽 2023-04-07 CN disclosed
CN-112204059-B Hydrogenated product of block copolymer, resin composition, and various uses thereof 株式会社可乐丽 2023-02-21 CN disclosed
EP-3653651-B1 BLOCK COPOLYMER HYDROGENATE, RESIN COMPOSITION, AND APPLICATIONS THEREOF KURARAY CO (JP) 2021-08-11 EP disclosed
CN-113227290-A Silane compound and composition thereof 引能仕株式会社 2021-08-06 CN disclosed
US-20210122868-A1 HYDROGENATED BLOCK COPOLYMER, RESIN COMPOSITION, PRESSURE-SENSITIVE ADHESIVE, ADHESIVE, MOLDED OBJECT, LIQUID-PACKAGING CONTAINER, MEDICAL TOOL, MEDICAL TUBE, CORNER MEMBER FOR WEATHER SEAL, AND WEATHER SEAL KURARAY CO., LTD. (JP) 2021-04-29 US disclosed
CN-110945034-B Hydrogenated product of block copolymer, resin composition, and various uses thereof 株式会社可乐丽 2021-03-26 CN disclosed
US-10927211-B2 Block copolymer hydrogenate, resin composition, and applications thereof KURARAY CO., LTD. (JP) 2021-02-23 US disclosed
EP-0560554-A2 Antitumor compositions and methods of treatment ELI LILLY AND COMPANY (US) 1993-09-15 EP disclosed
US-5169860-A Benzofuran or benzothiophene arylsulfonylureas ELI LILLY AND COMPANY (US) 1992-12-08 US disclosed
US-5158956-A Administering serotonin receptor agonist ELI LILLY AND COMPANY (US) 1992-10-27 US disclosed
EP-0498590-A1 Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes ELI LILLY AND COMPANY (US) 1992-08-12 EP disclosed
US-5096908-A 5-HT1A agonist ELI LILLY AND COMPANY (US) 1992-03-17 US disclosed
EP-0471515-A1 Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes and 3-aminothiochromanes ELI LILLY AND COMPANY (US) 1992-02-19 EP disclosed
EP-0458731-A1 Random copolymers and crosslinked products of te same MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1991-11-27 EP disclosed
EP-0455510-A2 Use of 5-HT1A receptor agonist compounds for inhibiting gastric acid secretion ELI LILLY AND COMPANY (US) 1991-11-06 EP disclosed
EP-0385658-A1 Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes ELI LILLY AND COMPANY (US) 1990-09-05 EP disclosed
US-4260803-A FIREPROOFING, HERBICIDES, FUNGICIDES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed