Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724753 | 0.90 | BRAF (0.33) | SCDNTRK1BRAFHTR2CHTR2B | |
| SCHEMBL4723187 | 0.88 | MAPT (0.34) | SCDFPR1FPR2KMT2AKDM4E | |
| SCHEMBL4719384 | 0.86 | MAPT (0.34) | SCDFPR1FPR2KMT2AKDM4E | |
| SCHEMBL4722630 | 0.84 | F10 (0.31) | SCDFPR1FPR2KMT2AKDM4E | |
| SCHEMBL4719755 | 0.83 | MAPT (0.35) | SCDFPR1FPR2KMT2AKDM4E | |
| SCHEMBL4719300 | 0.82 | BRD4 (0.35) | SCDFPR1FPR2HSD17B1HSD17B2 | |
| SCHEMBL4720527 | 0.82 | SCD (0.34) | SCDFPR1FPR2KDM4EHSD17B1 | |
| SCHEMBL4765721 | 0.80 | PDE4A (0.36) | SCDKMT2AKDM4EMEN1 | |
| SCHEMBL4719449 | 0.80 | PDE4A (0.36) | SCDKMT2AKDM4EMEN1 | |
| SCHEMBL4720876 | 0.80 | CYP11B1 (0.33) | NTRK1HTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |