Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CBS | P35520 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804016 | 0.92 | ESR1 (0.58) | CYP19A1ESR1ESR2SMN1; SMN2LMNA | |
| SCHEMBL30555701 | 0.85 | ESR2 (0.73) | CYP19A1ESR1ESR2MAOB | |
| SCHEMBL571732 | 0.85 | ESR2 (0.73) | CYP19A1ESR1ESR2MAOB | |
| SCHEMBL2029052 | 0.85 | ESR2 (0.73) | CYP19A1ESR1ESR2MAOB | |
| SCHEMBL14124895 | 0.78 | ESR2 (0.55) | CYP19A1ESR1ESR2CYP3A4MAPT | |
| SCHEMBL11396242 | 0.78 | ESR1 (0.55) | CYP19A1ESR1ESR2MAOBCYP3A4 | |
| SCHEMBL4799817 | 0.76 | POLB (0.68) | CYP19A1SMN1; SMN2CYP2C19CYP3A4CBS | |
| SCHEMBL29397268 | 0.75 | CYP19A1 (0.57) | CYP19A1ESR1ESR2SMN1; SMN2LMNA | |
| SCHEMBL30638795 | 0.75 | CYP19A1 (0.57) | CYP19A1ESR1ESR2SMN1; SMN2LMNA | |
| SCHEMBL28690004 | 0.74 | CYP19A1 (1.00) | CYP19A1ESR2MAOBCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809627-B2 | Plant isoflavone and isoflavanone O-methyltransferase genes | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20080317880-A1 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION | 2008-12-25 | — | — | US | disclosed |
| WO-2008022265-A2 | PLANT ISOFLAVONE AND ISOFLAVANONE O-METHYLTRANSFERASE GENES | THE SAMUEL ROBERTS NOBLE FOUNDATION, INC. (US) | 2008-02-21 | — | — | WO | disclosed |