Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30638795 | 1.00 | CYP19A1 (0.57) | CYP19A1MAOBESR1ESR2CYP3A4 | |
| SCHEMBL17637164 | 0.90 | KDM4E (0.58) | CYP19A1MAOBESR1ESR2CYP3A4 | |
| SCHEMBL11377219 | 0.83 | CYP19A1 (0.56) | CYP19A1MAOBCYP3A4LMNACYP2C19 | |
| SCHEMBL17637148 | 0.83 | KDM4E (0.54) | CYP19A1MAOBESR1ESR2CYP3A4 | |
| SCHEMBL17637561 | 0.81 | KDM4E (0.67) | CYP19A1CYP3A4LMNACYP2C19SMN1; SMN2 | |
| SCHEMBL4423401 | 0.78 | ESR2 (0.57) | CYP19A1MAOBESR2CYP3A4SMN1; SMN2 | |
| SCHEMBL4725052 | 0.75 | CYP19A1 (0.59) | CYP19A1MAOBESR1ESR2CYP3A4 | |
| SCHEMBL28486339 | 0.75 | CYP19A1 (0.50) | CYP19A1MAOBCYP3A4LMNACYP2C19 | |
| SCHEMBL16376660 | 0.75 | ESR1 (0.55) | CYP19A1MAOBESR1ESR2CYP3A4 | |
| SCHEMBL28414867 | 0.75 | ESR2 (0.53) | CYP19A1MAOBESR2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036040-A1 | SYNTHESIS OF SMALL MOLECULES INSPIRED BY PHOMOXANTHONE A | WORCESTER POLYTECHNIC INSTITUTE (US) | 2022-02-17 | — | — | WO | disclosed |
| US-20220048879-A1 | Synthesis of small molecules inspired by Phomoxanthone A | WORCESTER POLYTECHNIC INSTITUTE | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048879-A1 | Synthesis of small molecules inspired by Phomoxanthone A | ERG28, SQLE, PHKA1 | CYP19A1 129/4885MAOB 674/4885ESR1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.