Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 16/20 | 0.35 |
| ▸ | BRAF | P15056 | 16/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726702 | 0.86 | PTPN1 (0.38) | F7F2F9F10PLAU | |
| SCHEMBL4729468 | 0.84 | RAF1 (0.36) | RAF1BRAF | |
| SCHEMBL4728030 | 0.84 | MAPK14 (0.42) | POLQRAF1BRAFTP53MAPT | |
| SCHEMBL4730567 | 0.83 | TRPV1 (0.40) | F7F2F9F10PLAU | |
| SCHEMBL4781974 | 0.81 | PSEN1 (0.39) | POLQRAF1BRAF | |
| SCHEMBL4780832 | 0.80 | LMNA (0.42) | RAF1BRAFMAPT | |
| SCHEMBL4780311 | 0.80 | KDM4E (0.38) | RAF1BRAFMAPT | |
| SCHEMBL4726226 | 0.79 | RAF1 (0.46) | RAF1BRAFTP53SMN1; SMN2 | |
| SCHEMBL4784063 | 0.79 | RAF1 (0.36) | POLQRAF1BRAF | |
| SCHEMBL4726266 | 0.79 | RAF1 (0.35) | F7F2F9F10PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |