Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | FABP7 | O15540 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155140 | 0.85 | ALDH1A1 (0.57) | NPC1RAB9AATMFFAR1ALDH1A1 | |
| SCHEMBL23533686 | 0.83 | TAAR1 (0.54) | TAAR1MAOBKMT2AALDH1A1L3MBTL1 | |
| Phenethylamine SCHEMBL22129843 | 0.83 | TAAR1 (0.84) | TAAR1MAOB | |
| Benzyl Carbamate SCHEMBL4910897 | 0.80 | CA1 (0.57) | NPC1RAB9AATMMEN1KMT2A | |
| Bromoethane SCHEMBL9571773 | 0.79 | ALDH1A1 (0.51) | NPC1RAB9AATMKMT2AFFAR1 | |
| SCHEMBL22028110 | 0.79 | LTA4H (0.58) | NPC1RAB9AATMALDH1A1FABP7 | |
| SCHEMBL1521953 | 0.79 | LTA4H (0.58) | NPC1RAB9AATMALDH1A1FABP7 | |
| SCHEMBL22028109 | 0.79 | LTA4H (0.58) | NPC1RAB9AATMALDH1A1FABP7 | |
| SCHEMBL6644102 | 0.79 | LTA4H (0.58) | NPC1RAB9AATMALDH1A1FABP7 | |
| Benzyl Carbamate SCHEMBL4725135 | 0.78 | RAB9A (0.51) | NPC1RAB9AATMFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006044-A2 | SUBSTITUTED ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-10 | — | — | WO | disclosed |