Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777606 | 1.00 | IKBKB (0.34) | IKBKBAPOBEC3AAPOBEC3GPDE4DSYK | |
| SCHEMBL4793400 | 0.94 | KDM4E (0.36) | IKBKBPDE4DSYKSLC6A9KDM4E | |
| SCHEMBL4793397 | 0.94 | KDM4E (0.36) | IKBKBPDE4DSYKSLC6A9KDM4E | |
| SCHEMBL14291286 | 0.93 | IKBKB (0.33) | IKBKBAPOBEC3AAPOBEC3GPDE4DSYK | |
| SCHEMBL4148687 | 0.89 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYK | |
| SCHEMBL4148693 | 0.89 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYK | |
| Ammonia Solution, Strong SCHEMBL4153546 | 0.88 | APOBEC3A (0.34) | APOBEC3AAPOBEC3GSYK | |
| Ammonia Solution, Strong SCHEMBL4153549 | 0.88 | APOBEC3A (0.34) | APOBEC3AAPOBEC3GSYK | |
| SCHEMBL14291019 | 0.88 | KDM4E (0.36) | PDE4DSYKSLC6A9KDM4EHTT | |
| SCHEMBL4726527 | 0.87 | ALDH1A1 (0.39) | APOBEC3AAPOBEC3GSYKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | claimed |
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |