Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19279137 | 0.80 | GFER (0.47) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL9623026 | 0.79 | USP2 (0.47) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11732994 | 0.77 | GFER (0.57) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL11742170 | 0.71 | GFER (0.61) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL4725291 | 0.71 | GFER (0.50) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL4029160 | 0.71 | GFER (0.47) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL19279306 | 0.70 | ALOX15 (0.59) | GFERHSD17B10ALDH1A1KMT2AALOX15 | |
| SCHEMBL11742569 | 0.70 | GFER (0.58) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL148202 | 0.69 | GFER (0.57) | GFERHSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL4029984 | 0.69 | GFER (0.50) | GFERHSD17B10ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |