Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159364 | 0.74 | CDK9 (0.40) | CDK9CCNT1SLC6A2SLC6A3 | |
| SCHEMBL2778860 | 0.71 | HTR6 (0.67) | SLC6A4HTR6HTR7HTR2AHTR2C | |
| SCHEMBL9268634 | 0.67 | NR4A2 (0.68) | SLC6A4HTR1AHTR6HTR7GPR84 | |
| SCHEMBL6333063 | 0.66 | CDK9 (0.41) | CDK9CCNT1 | |
| SCHEMBL7826159 | 0.65 | KDR (0.68) | SLC6A4IGF1RPDGFRBKITPDGFRA | |
| SCHEMBL14440430 | 0.65 | SIRT2 (0.63) | SLC6A4IGF1RPDGFRBKITPDGFRA | |
| SCHEMBL7195501 | 0.65 | SIRT2 (0.63) | SLC6A4IGF1RPDGFRBKITPDGFRA | |
| Ethylene SCHEMBL6640393 | 0.65 | SLC6A4 (0.57) | SLC6A4HTR1AHTR6HTR7GPR84 | |
| SCHEMBL11573397 | 0.64 | NR4A2 (0.64) | SLC6A4HTR1AHTR7GPR84MAP3K14 | |
| SCHEMBL5426923 | 0.64 | HTR1A (0.53) | SLC6A4HTR1AHTR6HTR7GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015516-A1 | FUSED TRICYCLIC HETEROCYCLES FOR THE TREATMENT OF SCHIZOPHRENIA | PFIZER PRODUCTS INC. (US) | 2008-02-07 | — | — | WO | disclosed |