Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.32 |
| ▸ | TET3 | O43151 | 1/20 | 0.32 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL5595699 | 1.00 | TGFBR1 (0.45) | TGFBR1TDP1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL147269 | 1.00 | TGFBR1 (0.45) | TGFBR1TDP1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL9815885 | 1.00 | TGFBR1 (0.45) | TGFBR1TDP1TSHROR51E2TET2 | |
| Methacrylic Acid SCHEMBL3974705 | 0.87 | TGFBR1 (0.41) | TGFBR1TDP1TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL1480102 | 0.87 | TGFBR1 (0.41) | TGFBR1TDP1TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL4158756 | 0.87 | TGFBR1 (0.41) | TGFBR1TDP1TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL514764 | 0.87 | TGFBR1 (0.41) | TGFBR1TDP1TSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL2032735 | 0.85 | TGFBR1 (0.39) | TGFBR1TDP1TSHR | |
| Methacrylic Acid SCHEMBL8383578 | 0.85 | TGFBR1 (0.39) | TGFBR1TDP1TSHR | |
| Methacrylic Acid SCHEMBL51594 | 0.85 | TGFBR1 (0.39) | TGFBR1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872292-B2 | Cationically and radiation curable composition | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230320941-A1 | DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM | SDI LIMITED (AU) | 2023-10-12 | — | — | US | disclosed |
| EP-4196077-A1 | DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM | Sdi Limited (AU) | 2023-06-21 | — | — | EP | disclosed |
| US-20230175067-A1 | PROGNOSIS METHOD FOR RENAL CELL CANCER | NATIONAL CANCER CENTER (JP) | 2023-06-08 | — | — | US | disclosed |
| EP-3346015-B1 | PROGNOSIS METHOD FOR RENAL CELL CANCER | NAT CANCER CT (JP) | 2022-05-11 | — | — | EP | disclosed |
| WO-2022032351-A1 | DENTAL COMPOSITION, KIT AND METHOD FOR USE AS ALTERNATIVE RESTORATIVE MATERIAL TO DENTAL AMALGAM | SDI LIMITED (AU) | 2022-02-17 | — | — | WO | disclosed |
| US-20220047465-A1 | DENTAL COMPOSITION | GC CORPORATION (JP) | 2022-02-17 | — | — | US | disclosed |
| EP-3515396-B1 | CATIONICALLY AND RADIATION CURABLE COMPOSITION | 3M INNOVATIVE PROPERTIES CO (US) | 2022-01-05 | — | — | EP | disclosed |
| US-11142801-B2 | Tumor determination method | JAPANESE FOUNDATION FOR CANCER RESEARCH (JP) | 2021-10-12 | — | — | US | disclosed |
| US-20210276243-A1 | THREE-DIMENSIONAL PRINTING COMPOSITION AND METHOD OF PRODUCING DENTAL ARTICLE | GC CORPORATION (JP) | 2021-09-09 | — | — | US | disclosed |
| WO-2006084769-A1 | CARBOXYLIC ACID CONTAINING DISPERSANTS FOR COMPOSITES | DENTSPLY DETREY GMBH (DE) | 2006-08-17 | — | — | WO | disclosed |
| EP-1498098-B1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2006-05-03 | — | — | EP | disclosed |
| US-20060069181-A1 | Dental adhesive composition | 3M ESPE AG | 2006-03-30 | — | — | US | disclosed |
| EP-1639987-A1 | Dental adhesive composition | 3M Espe AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005004819-A1 | ADHESIVE COMPOSITION WITH DECREASED POLARITY UPON POLYMERIZATION | 3M ESPE AG (DE) | 2005-01-20 | — | — | WO | disclosed |
| EP-1498098-A1 | Adhesive composition with decreased polarity upon polymerization | 3M ESPE AG (DE) | 2005-01-19 | — | — | EP | disclosed |
| EP-0948955-B1 | POLYMERIZABLE DENTAL COMPOSITION | KURARAY CO (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6191191-B1 | USED AS BONDING AGENT, COMPOSITE RESIN, ADHESIVE AGENT, PRIMER AND OPAQUE PRIMER FOR DENTAL USE; LIGHT RESISTANCE; ADHESION TO TOOTH SURFACE AND METALS; COLORFASTNESS | KURARAY CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0948955-A1 | POLYMERIZABLE DENTAL COMPOSITION | KURARAY CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-4838789-A | EXTERIOR SHIELD AND PHOTOPOLYMERIZABLE RESIN | G-C DENTAL INDUSTRIAL CORP. (JP) | 1989-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11872292-B2 | Cationically and radiation curable composition | RAD51, SMARCA1, SMARCA4 | TGFBR1 606/4885TDP1 665/4885TSHR 4421/4885 |
| US-20220047465-A1 | DENTAL COMPOSITION | TAS2R45, TAS2R40, TAS2R42 | TGFBR1 4638/4885TDP1 527/4885TSHR 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.