Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4216040 | 0.84 | TSHR (0.57) | ALDH1A1FOLH1TSHRMRGPRX4ALOX15 | |
| SCHEMBL166927 | 0.83 | FOLH1 (0.66) | ALDH1A1ADRB2HTTFOLH1MAPT | |
| SCHEMBL29975597 | 0.83 | FOLH1 (0.66) | ALDH1A1ADRB2HTTFOLH1MAPT | |
| SCHEMBL27705072 | 0.82 | PTPN1 (0.49) | ALDH1A1FOLH1KDM4EMRGPRX4HMGB1 | |
| SCHEMBL8702953 | 0.82 | FOLH1 (0.63) | ALDH1A1ADRB2HTTFOLH1MAPT | |
| Hydrochloric Acid SCHEMBL7699238 | 0.82 | FOLH1 (0.63) | ALDH1A1ADRB2HTTFOLH1MAPT | |
| SCHEMBL19492443 | 0.82 | ALDH1A1 (0.56) | ALDH1A1ADRB2HTTLMNATSHR | |
| SCHEMBL301121 | 0.81 | HMGB1 (0.67) | ALDH1A1ADRB2HTTFOLH1MAPT | |
| SCHEMBL3001321 | 0.81 | FOLH1 (0.55) | ALDH1A1ADRB2HTTFOLH1MAPT | |
| SCHEMBL27912539 | 0.81 | MRGPRX4 (0.46) | ALDH1A1FOLH1TSHRMRGPRX4HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014505-A2 | BLENDS FOR IMPROVED SOLUBILIZATION OF ACTIVE AND FUNCTIONAL ORGANIC COMPOUNDS | ISP INVESTMENTS INC. (US) | 2008-01-31 | — | — | WO | claimed |