Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166927 | 0.98 | FOLH1 (0.66) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| SCHEMBL29975597 | 0.98 | FOLH1 (0.66) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL7699238 | 0.96 | FOLH1 (0.63) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| SCHEMBL8698803 | 0.94 | FOLH1 (0.58) | FOLH1ALDH1A1ADRB2LMNAKDM4E | |
| SCHEMBL70392 | 0.89 | FOLH1 (0.76) | FOLH1ALDH1A1ADRB2KDM4ESMN1; SMN2 | |
| SCHEMBL30365583 | 0.89 | FOLH1 (0.76) | FOLH1ALDH1A1ADRB2KDM4ESMN1; SMN2 | |
| SCHEMBL7764255 | 0.87 | TSHR (0.72) | FOLH1ALDH1A1ADRB2LMNAHTT | |
| SCHEMBL20162476 | 0.86 | FOLH1 (0.61) | FOLH1ALDH1A1ADRB2SMN1; SMN2MAPT | |
| SCHEMBL11710027 | 0.86 | FOLH1 (0.61) | FOLH1ALDH1A1ADRB2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8327538 | 0.86 | KMT2A (0.56) | FOLH1ALDH1A1ADRB2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834468-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANALGESICS TREATING RHEUMATIC DISEASE, BONE DISORDER, INJURIES | ZENECA LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |