Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | XIAP | P98170 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956347 | 0.92 | OPRM1 (0.52) | OPRM1OPRD1OPRK1SLC6A2XIAP | |
| SCHEMBL11091524 | 0.88 | SLC6A2 (0.63) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL31184433 | 0.88 | SLC6A2 (0.63) | OPRM1OPRD1OPRK1SLC6A2 | |
| SCHEMBL3635117 | 0.87 | OPRM1 (0.67) | OPRM1OPRD1OPRK1XIAP | |
| SCHEMBL4965647 | 0.85 | PREP (0.57) | XIAP | |
| SCHEMBL14479875 | 0.84 | OPRM1 (0.53) | OPRM1OPRD1OPRK1SLC6A2XIAP | |
| SCHEMBL10297418 | 0.84 | OPRM1 (0.53) | OPRM1OPRD1OPRK1SLC6A2XIAP | |
| SCHEMBL10297462 | 0.84 | OPRM1 (0.53) | OPRM1OPRD1OPRK1SLC6A2XIAP | |
| SCHEMBL4959360 | 0.82 | ACE (0.51) | OPRM1OPRD1OPRK1XIAP | |
| SCHEMBL10297414 | 0.82 | ACE (0.51) | OPRM1OPRD1OPRK1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020085-A2 | USE OF CHLORO- AND FLUOROMETHYL KETONE DERIVATIVES IN ANTI-VIRAL THERAPY | VIROLOGIK GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |