Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.57 |
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | CMA1 | P23946 | 9/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956347 | 0.86 | OPRM1 (0.52) | CMA1XIAP | |
| SCHEMBL11517511 | 0.85 | PREP (0.70) | PREPRENACECMA1CTRB1 | |
| SCHEMBL4726416 | 0.85 | OPRM1 (0.55) | XIAP | |
| SCHEMBL9699165 | 0.83 | CMA1 (0.65) | PREPACECMA1 | |
| SCHEMBL9699161 | 0.83 | CMA1 (0.65) | PREPACECMA1 | |
| SCHEMBL11517201 | 0.83 | PREP (0.68) | PREPRENACECMA1CTRB1 | |
| SCHEMBL7319431 | 0.82 | REN (0.65) | PREPRENACECMA1CTRB1 | |
| SCHEMBL22209468 | 0.81 | PREP (0.72) | PREPACEELANEACE2 | |
| SCHEMBL7871516 | 0.81 | PREP (0.72) | PREPACEELANEACE2 | |
| SCHEMBL7334484 | 0.81 | PREP (0.72) | PREPACEELANEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804558-B1 | TRIPEPTIDYL AMINOPEPTIDASE | NOVOZYMES AS (DK) | 2008-01-23 | — | — | EP | disclosed |
| US-5821104-A | DNA CONSTRUCT ENCODING THE ENZYME AND REDUCING PRODUCTION IN CELLS WHERE THE ACTICITY IS UNDESIRABLE | NOVO NORDISK A/S (DK) | 1998-10-13 | — | — | US | disclosed |
| EP-0804558-A2 | TRIPEPTIDYL AMINOPEPTIDASE | NOVO NORDISK A/S (DK) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996014404-A1 | TRIPEPTIDYL AMINOPEPTIDASE | NOVO NORDISK A/S (DK) | 1996-05-17 | — | — | WO | disclosed |
| WO-1994025581-A1 | MODIFIED RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR | SOUTHERN SYDNEY AREA HEALTH SERVICE (AU) | 1994-11-10 | — | — | WO | disclosed |