Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | XIAP | P98170 | 5/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726416 | 0.92 | OPRM1 (0.55) | OPRM1OPRD1OPRK1XIAPSLC6A2 | |
| SCHEMBL4959360 | 0.91 | ACE (0.51) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL14479876 | 0.91 | ACE (0.51) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL10297414 | 0.91 | ACE (0.51) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL10297452 | 0.90 | XIAP (0.52) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL10297426 | 0.90 | XIAP (0.52) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL15231343 | 0.89 | SLC6A2 (0.59) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL15231906 | 0.89 | SLC6A2 (0.59) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL15231898 | 0.89 | SLC6A2 (0.59) | OPRM1OPRD1OPRK1XIAPCMA1 | |
| SCHEMBL4965647 | 0.86 | PREP (0.57) | XIAPCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402561-B2 | Compositions and methods for inhibiting abnormal cell growth | CLAWNOR, INC. (US) | 2008-07-22 | — | — | US | disclosed |
| WO-2005087251-A1 | COMPOSITIONS AND METHODS FOR INHIBITING ABNORMAL CELL GROWTH | CLAWNOR, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050209150-A1 | Compositions and methods for inhibiting abnormal cell growth | CLAWNOR, INC. | 2005-09-22 | — | — | US | disclosed |