Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122818 | 0.86 | LMNA (0.42) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL640184 | 0.86 | LMNA (0.42) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL11424155 | 0.86 | LMNA (0.42) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL2115466 | 0.85 | LMNA (0.37) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL1267825 | 0.85 | LMNA (0.37) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL3073599 | 0.84 | LMNA (0.46) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL517269 | 0.84 | LMNA (0.46) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL319408 | 0.84 | LMNA (0.46) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL2635052 | 0.84 | LMNA (0.46) | AKR1B1LMNAL3MBTL1TDP1USP2 | |
| SCHEMBL2635114 | 0.82 | AKR1B1 (0.34) | AKR1B1LMNAL3MBTL1TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011168-A2 | GLYCOSYLATED PEPTIDE ANTAGONISTS OF THE BRADYKININ B1 RECEPTOR | AMGEN INC. (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008011168-A2 | GLYCOSYLATED PEPTIDE ANTAGONISTS OF THE BRADYKININ B1 RECEPTOR | AMGEN INC. (US) | 2008-01-24 | — | — | WO | disclosed |