Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 2/20 | 0.32 |
| ▸ | TK1 | P04183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25456621 | 0.88 | RNASE1 (0.39) | RNASE1ALDH1A1CYP1A2MAPTALOX15 | |
| SCHEMBL4730469 | 0.84 | ALDH1A1 (0.46) | RNASE1ALDH1A1HTTPPM1BPOLB | |
| SCHEMBL4731815 | 0.83 | RNASE1 (0.44) | RNASE1ALDH1A1HTTPPM1BPOLB | |
| SCHEMBL29897125 | 0.79 | RNASE1 (0.68) | RNASE1POLBNPC1TK1 | |
| SCHEMBL4731006 | 0.78 | RNASE1 (0.60) | RNASE1TK1 | |
| SCHEMBL4731003 | 0.78 | RNASE1 (0.60) | RNASE1TK1 | |
| SCHEMBL12352467 | 0.77 | RNASE1 (0.58) | RNASE1ALDH1A1HTTPPM1BPOLB | |
| SCHEMBL2623806 | 0.77 | RNASE1 (0.58) | RNASE1ALDH1A1HTTPPM1BPOLB | |
| SCHEMBL9098216 | 0.77 | KMT2A (0.39) | RNASE1ALDH1A1HTTPPM1BPOLB | |
| SCHEMBL9098220 | 0.77 | KMT2A (0.39) | RNASE1ALDH1A1HTTPPM1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037568-A2 | REVERSIBLE TERMINATORS FOR EFFICIENT SEQUENCING BY SYNTHESIS | QUIATECH AB (SE) | 2008-04-03 | — | — | WO | disclosed |