Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26233449 | 0.88 | RNASE1 (0.42) | RNASE1 | |
| SCHEMBL9443821 | 0.87 | RNASE1 (0.48) | RNASE1 | |
| SCHEMBL21563855 | 0.87 | RNASE1 (0.48) | RNASE1 | |
| SCHEMBL537189 | 0.87 | RNASE1 (0.48) | RNASE1 | |
| SCHEMBL21563858 | 0.85 | TOP2A (0.43) | RNASE1TYMS | |
| SCHEMBL21545839 | 0.85 | TOP2A (0.43) | RNASE1TYMS | |
| SCHEMBL4731815 | 0.84 | RNASE1 (0.44) | ALDH1A1HTTRNASE1NPC1PPM1B | |
| SCHEMBL4727124 | 0.84 | RNASE1 (0.43) | ALDH1A1HTTRNASE1NPC1PPM1B | |
| SCHEMBL25456618 | 0.83 | TK1 (0.38) | ALDH1A1RNASE1 | |
| SCHEMBL29897125 | 0.81 | RNASE1 (0.68) | RNASE1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037568-A2 | REVERSIBLE TERMINATORS FOR EFFICIENT SEQUENCING BY SYNTHESIS | QUIATECH AB (SE) | 2008-04-03 | — | — | WO | disclosed |