Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19123985 | 1.00 | CTSL (0.57) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL18030283 | 0.96 | BCHE (0.57) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL751179 | 0.95 | CTSL (0.55) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL254960 | 0.89 | CTSL (0.58) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL9392638 | 0.88 | CTSL (0.57) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL16907368 | 0.88 | CTSL (0.60) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL19325105 | 0.88 | BCHE (0.56) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL18116765 | 0.88 | BCHE (0.56) | CTSLCTSSBCHEACHESIRT2 | |
| SCHEMBL3624634 | 0.88 | FOLH1 (0.55) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL3624630 | 0.88 | FOLH1 (0.55) | CTSLCTSSSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458188-B2 | Efficient peptide couplings and their use in the synthesis and isolation of a cyclopenta (G) quinazoline trisodium salt | BTG INTERNATIONAL LIMITED (GB) | 2016-10-04 | — | — | US | disclosed |
| EP-2655398-B1 | EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT | BTG INT LTD (GB) | 2016-08-24 | — | — | EP | disclosed |
| EP-2837384-A1 | Glutathione based delivery system | Industrial Technology Research Institute (TW) | 2015-02-18 | — | — | EP | disclosed |
| WO-2012087888-A2 | EFFICIENT PEPTIDE COUPLINGS AND THEIR USE IN THE SYNTHESIS AND ISOLATION OF A CYCLOPENTA (G) QUINAZOLINE TRISODIUM SALT | ONYX PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012003436-A1 | METHODS FOR TREATING POST TRAUMATIC STRESS DISORDER | AZEVAN PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| EP-1891962-A1 | Glutathione based delivery system | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-02-27 | — | — | EP | disclosed |