SCHEMBL4727402

SCHEMBL4727402

CC(C)C(CN)C(C)C.[NaH]

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979 0.96
Bromide SCHEMBL1999327 0.92 ALDH1A1 (0.44) ALDH1A1TAAR1
Fluoride SCHEMBL73856 0.92 ALDH1A1 (0.44) ALDH1A1TAAR1
SCHEMBL3210302 0.92 ALDH1A1 (0.44) ALDH1A1TAAR1
Hydrochloric Acid SCHEMBL366444 0.92 ALDH1A1 (0.44) ALDH1A1TAAR1
Fluoride SCHEMBL1025918 0.92 ALDH1A1 (0.44) ALDH1A1TAAR1
Ammonia Solution, Strong SCHEMBL6136995 0.92 ALDH1A1 (0.44) ALDH1A1TAAR1
SCHEMBL4787789 0.86 ALDH1A1 (0.39) ALDH1A1
Trimethylammonium SCHEMBL4940105 0.86 ALDH1A1 (0.39) ALDH1A1
Dimethylamine SCHEMBL6889985 0.83 ALDH1A1 (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008096129-A1 NITROGEN CONTAINING HETROCYCLIC COMPOUNDS USEFUL AS BIFUNCTIONAL MODULATORS OF M3 RECEPTORS AND BETA- 2 RECEPTORS ARGENTA DISCOVERY LTD (GB) 2008-08-14 WO disclosed
WO-2008023157-A1 NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS ARGENTA DISCOVERY LIMITED (GB) 2008-02-28 WO disclosed
WO-2008017827-A2 AZOLE AND THIAZOLE DERIVATIVES AND THEIR USES ARGENTA DISCOVERY LIMITED (GB) 2008-02-14 WO disclosed