Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL6136995 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TAAR1 | |
| Bromide SCHEMBL1999327 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TAAR1 | |
| Fluoride SCHEMBL1025918 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL366444 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TAAR1 | |
| SCHEMBL4727402 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TAAR1 | |
| Fluoride SCHEMBL73856 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TAAR1 | |
| Trimethylammonium SCHEMBL4940105 | 0.86 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL4787789 | 0.86 | ALDH1A1 (0.39) | ALDH1A1 | |
| Dimethylamine SCHEMBL6889985 | 0.83 | ALDH1A1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048899-A1 | PROCESS FOR PREPARING ROSUVASTATIN CALCIUM | AUROBINDO PHARMA LTD (IN) | 2010-02-25 | — | — | US | claimed |
| EP-2079712-A2 | AN IMPROVED PROCESS FOR PREPARING ROSUVASTATIN CALCIUM | AUROBINDO PHARMA LIMITED (IN) | 2009-07-22 | — | — | EP | claimed |
| WO-2008053334-A2 | AN IMPROVED PROCESS FOR PREPARING ROSUVASTATIN CALCIUM | AUROBINDO PHARMA LIMITED (IN) | 2008-05-08 | — | — | WO | claimed |
| CN-116615427-A | Substituted macrocyclic compounds and related methods of treatment | 阿尔克姆斯有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | GOSSAMER BIO SERVICES INC (US) | 2021-05-13 | — | — | US | disclosed |
| WO-2019200120-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | LYCERA CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |
| US-8318933-B2 | Process for preparing rosuvastatin calcium | AUROBINDO PHARMA LTD (IN) | 2012-11-27 | — | — | US | disclosed |
| EP-1280764-B1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC (CA) | 2010-11-24 | — | — | EP | disclosed |
| US-20100048899-A1 | PROCESS FOR PREPARING ROSUVASTATIN CALCIUM | AUROBINDO PHARMA LTD (IN) | 2010-02-25 | — | — | US | disclosed |
| EP-2079712-A2 | AN IMPROVED PROCESS FOR PREPARING ROSUVASTATIN CALCIUM | AUROBINDO PHARMA LIMITED (IN) | 2009-07-22 | — | — | EP | disclosed |
| US-20090181971-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. | 2009-07-16 | — | — | US | disclosed |
| US-7288567-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2007-10-30 | — | — | US | disclosed |
| US-20070244133-A1 | Thienopyrimidines and Thiazolopyrimidines for Use in Medicine | ASTRAZENECA AB (SE) | 2007-10-18 | — | — | US | disclosed |
| EP-1524262-A1 | Inhibitors of histone deacetylase | Methylgene, Inc. (CA) | 2005-04-20 | — | — | EP | disclosed |
| EP-1280764-A2 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2003-02-05 | — | — | EP | disclosed |
| US-20020115826-A1 | Inhibitors of histone deacetylase | 92229129 QUEBEC INC. (CA) | 2002-08-22 | — | — | US | disclosed |
| WO-2001070675-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2001-09-27 | — | — | WO | disclosed |
| EP-0180399-B1 | ANTI-TUMOR 4-HYDROXY-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-4711895-A | 4-hydroxy-2-cyclopentenone, process for production thereof, pharmaceutical composition comprising it | TEIJIN LIMITED (JP) | 1987-12-08 | — | — | US | disclosed |
| EP-0180399-A2 | Anti-tumor 4-Hydroxy-2-cyclopentenones | TEIJIN LIMITED (JP) | 1986-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048899-A1 | PROCESS FOR PREPARING ROSUVASTATIN CALCIUM | CACNA1I, CACNA1S, CACNA1F | ALDH1A1 2957/4885TAAR1 4642/4885 |
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ULK1, PHKG2, PHKG1 | ALDH1A1 2060/4885TAAR1 4185/4885 |
| US-20020115826-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC5, HDAC3 | ALDH1A1 796/4885TAAR1 4583/4885 |
| US-20070244133-A1 | Thienopyrimidines and Thiazolopyrimidines for Use in Medicine | CXCR4, CXCR1, CXCR3 | ALDH1A1 683/4885TAAR1 1021/4885 |
| US-20090181971-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC5, HDAC3 | ALDH1A1 796/4885TAAR1 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.