Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Z)-1,2-Diphenylethene SCHEMBL27365779 | 0.78 | NFE2L2 (0.60) | NFE2L2FBP1CYP19A1MAPTTAAR1 | |
| SCHEMBL11660719 | 0.76 | PDE7A (0.39) | MAPTMEN1KMT2APDE7APOLB | |
| SCHEMBL4555909 | 0.74 | ALDH5A1 (0.43) | MAPTPDE7AMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL14292160 | 0.73 | NFE2L2 (0.47) | NFE2L2FBP1CYP19A1MAPTTAAR1 | |
| SCHEMBL1578978 | 0.73 | MAPT (0.66) | NFE2L2FBP1CYP19A1MAPTMEN1 | |
| SCHEMBL5442818 | 0.73 | MAPT (0.66) | NFE2L2FBP1CYP19A1MAPTMEN1 | |
| SCHEMBL1578983 | 0.73 | MAPT (0.66) | NFE2L2FBP1CYP19A1MAPTMEN1 | |
| SCHEMBL27799509 | 0.73 | PDE7A (0.38) | MAPTMEN1KMT2APDE7APOLB | |
| SCHEMBL29594574 | 0.73 | MAPT (0.66) | NFE2L2FBP1CYP19A1MAPTMEN1 | |
| SCHEMBL28081567 | 0.72 | MAOB (0.42) | NFE2L2CYP19A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |