Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799509 | 0.82 | PDE7A (0.38) | ALDH5A1ABATPDE7ATDP1GPR35 | |
| SCHEMBL11660719 | 0.81 | PDE7A (0.39) | ALDH5A1ABATPDE7AERN1XDH | |
| SCHEMBL11494859 | 0.77 | PDE7A (0.36) | ALDH5A1ABATPDE7ATDP1GPR35 | |
| SCHEMBL2460904 | 0.77 | ALDH1A1 (0.47) | ERN1TDP1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4727465 | 0.74 | NFE2L2 (0.47) | PDE7ATDP1MAPK1SMN1; SMN2MAPT | |
| SCHEMBL9399032 | 0.73 | GPR35 (0.50) | PDE7ATDP1GPR35ALDH1A1HPGD | |
| SCHEMBL11826120 | 0.73 | PDE7A (0.43) | PDE7ATDP1GPR35ALDH1A1TSHR | |
| SCHEMBL872076 | 0.71 | PDE7A (0.46) | PDE7ATDP1GPR35ALDH1A1HPGD | |
| SCHEMBL27329527 | 0.71 | PDE7A (0.36) | ALDH5A1ABATPDE7AERN1VCAM1 | |
| SCHEMBL5841002 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736195-A | Nitrofuran hydrazone naphthalimide compound, and preparation method and application thereof | 西南大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-103333170-B | Benzimidazoles compound and application thereof | 清华大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-103333170-A | Benzimidazole compound and use thereof | UNIV TSINGHUA | 2013-10-02 | — | — | CN | disclosed |
| WO-2013033310-A1 | MODULATORS OF REV-ERB | KAMENECKA THEODORE MARK (US) | 2013-03-07 | — | — | WO | disclosed |
| EP-2137158-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES (PRMTS) | MethylGene Inc. (CA) | 2009-12-30 | — | — | EP | disclosed |
| CN-100526310-C | Cyclopropyl-thienyl-carboxamides useful as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-12 | — | — | CN | disclosed |
| WO-2008104077-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES (PRMTS) | METHYLGENE INC. (CA) | 2008-09-04 | — | — | WO | disclosed |
| US-7312179-B2 | Cyclopropyl-thienyl-carboxamide as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2007-12-25 | — | — | US | disclosed |
| EP-1556377-B1 | CYCLOPROPYL-THIENYL-CARBOXAMIDE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-28 | — | — | EP | disclosed |
| US-20060030567-A1 | Cyclopropyl-thienyl-carboxamide as fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-02-09 | — | — | US | disclosed |
| EP-0686141-B1 | NEW PROCESS FOR THE NITRATION OF AROMATIC COMPOUNDS IN MILD, NON-CORROSIVE CONDITIONS | INST NACIONAL DE ENGENHARIA E (PT) | 1998-12-09 | — | — | EP | disclosed |
| US-5760058-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| WO-1998012177-A1 | PYRROLIDINYL AND PYRROLINYL ETHYLAMINE COMPOUNDS AS KAPPA AGONISTS | PFIZER INC. (JP) | 1998-03-26 | — | — | WO | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0686141-A1 | NEW PROCESS FOR THE NITRATION OF AROMATIC COMPOUNDS IN MILD, NON-CORROSIVE CONDITIONS | INSTITUTO NACIONAL DE ENGENHARIA E TECNOLOGIA INDUSTRIAL (PT) | 1995-12-13 | — | — | EP | disclosed |
| CN-1104412-A | Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients | OTSUKA PHARMA CO LTD (JP) | 1995-06-28 | — | — | CN | disclosed |
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994019310-A1 | NEW PROCESS FOR THE NITRATION OF AROMATIC COMPOUNDS IN MILD, NON-CORROSIVE CONDITIONS | INSTITUTO NACIONAL DE ENGENHARIA E TECNOLOGIA INDUSTRIAL (PT) | 1994-09-01 | — | — | WO | disclosed |
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030567-A1 | Cyclopropyl-thienyl-carboxamide as fungicides | CBR3, CBR1, CYP8B1 | ALDH5A1 2513/4885ABAT 1836/4885PDE7A 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.