Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.49 |
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726236 | 0.96 | GABRA2 (0.47) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4730476 | 0.95 | CNR1 (0.45) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4729420 | 0.95 | CNR1 (0.46) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4728992 | 0.92 | CNR1 (0.45) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4779852 | 0.91 | KDM4E (0.48) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4784500 | 0.91 | CNR1 (0.44) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4728229 | 0.90 | KDM4E (0.47) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4876719 | 0.88 | KDM4E (0.45) | CNR1CNR2KDM4EMEN1MAPT | |
| SCHEMBL4728972 | 0.84 | MARS1 (0.48) | CNR1CNR2PPARA | |
| SCHEMBL4784498 | 0.82 | MARS1 (0.49) | CNR1CNR2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |