Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728229 | 0.92 | KDM4E (0.47) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4727572 | 0.91 | CNR1 (0.49) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4782013 | 0.91 | PDE4B (0.45) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4729420 | 0.90 | CNR1 (0.46) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4876719 | 0.90 | KDM4E (0.45) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4726236 | 0.89 | GABRA2 (0.47) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4730476 | 0.88 | CNR1 (0.45) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4728992 | 0.88 | CNR1 (0.45) | KDM4EMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL4730288 | 0.87 | CNR2 (0.42) | KDM4EMEN1MAPTKMT2ACNR1 | |
| SCHEMBL4784500 | 0.85 | CNR1 (0.44) | KDM4EMEN1MAPTKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |