SCHEMBL4727602 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	RAF1	P04049	10/20	0.42

▸	BRAF	P15056	9/20	0.42

▸	TRPV1	Q8NER1	3/20	0.39

▸	HDAC3	O15379	1/20	0.39

▸	HDAC6	Q9UBN7	1/20	0.39

▸	ADORA2A	P29274	1/20	0.38

▸	EPHA3	P29320	1/20	0.38

▸	FRK	P42685	1/20	0.38

▸	MAPK14	Q16539	1/20	0.38

▸	KDM4E	B2RXH2	1/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	LMNA	P02545	1/20	0.36

▸	MAPT	P10636	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4727533	0.93	RAF1 (0.41)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL4726088	0.89	RAF1 (0.41)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL4729210	0.87	TRPV1 (0.42)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL4729484	0.86	TRPV1 (0.41)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL4729212	0.86	TRPV1 (0.41)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL4726226	0.84	RAF1 (0.46)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL4726798	0.83	RAF1 (0.42)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL14292743	0.83	TRPV1 (0.39)	RAF1BRAFTRPV1HDAC3HDAC6
SCHEMBL4730164	0.83	MAPK14 (0.53)	RAF1BRAFEPHA3FRKMAPK14
SCHEMBL4781066	0.83	MAPK14 (0.55)	RAF1EPHA3FRKMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008021388-A1	HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS	KEMIA, INC. (US)	2008-02-21	—	—	WO	disclosed