Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728276 | 0.92 | MAPT (0.43) | ALPLTARBP2MAPTHSD17B10RAB9A | |
| SCHEMBL4726712 | 0.90 | MAPT (0.42) | ALPLTARBP2MAPTHSD17B10RAB9A | |
| SCHEMBL4731229 | 0.87 | MAPT (0.45) | ALPLTARBP2MAPTHSD17B10RAB9A | |
| SCHEMBL4729634 | 0.86 | KDM4E (0.40) | MAPTHSD17B10RAB9ANPC1POLB | |
| SCHEMBL4726914 | 0.85 | MAPT (0.39) | ALPLTARBP2MAPTHSD17B10RAB9A | |
| SCHEMBL4726897 | 0.84 | GAA (0.40) | ALPLMAPTHSD17B10RAB9ANPC1 | |
| SCHEMBL4726979 | 0.84 | SMN1; SMN2 (0.39) | ALPLTARBP2MAPTHSD17B10RAB9A | |
| SCHEMBL2171236 | 0.84 | L3MBTL1 (0.38) | ALPLTARBP2MAPTHSD17B10RAB9A | |
| SCHEMBL4729379 | 0.83 | GAA (0.40) | ALPLMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4731047 | 0.80 | MAPT (0.43) | ALPLTARBP2MAPTHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |