Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726712 | 0.90 | MAPT (0.42) | KDM4EPOLBHPGDNPSR1LMNA | |
| SCHEMBL4727728 | 0.86 | ALPL (0.44) | KDM4EPOLBALOX5TP53TSHR | |
| SCHEMBL4729379 | 0.85 | GAA (0.40) | KDM4EALDH1A1LMNATSHRNPC1 | |
| SCHEMBL4728706 | 0.85 | ALPL (0.43) | KDM4EPOLBALDH1A1GLAATM | |
| SCHEMBL2171236 | 0.84 | L3MBTL1 (0.38) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL2175776 | 0.83 | NPC1 (0.48) | KDM4EPOLBALDH1A1HPGDTP53 | |
| SCHEMBL4726914 | 0.83 | MAPT (0.39) | KDM4EPOLBHPGDNPSR1LMNA | |
| SCHEMBL4726897 | 0.83 | GAA (0.40) | KDM4EPOLBALDH1A1HPGDNPSR1 | |
| SCHEMBL4728276 | 0.83 | MAPT (0.43) | KDM4EPOLBNPSR1TSHRHSD17B10 | |
| SCHEMBL4726979 | 0.82 | SMN1; SMN2 (0.39) | KDM4EPOLBALOX5ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |