Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 10/20 | 0.39 |
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726979 | 0.92 | SMN1; SMN2 (0.39) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL4727728 | 0.92 | ALPL (0.44) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL4726712 | 0.92 | MAPT (0.42) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL4726914 | 0.89 | MAPT (0.39) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL4731229 | 0.88 | MAPT (0.45) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL4726897 | 0.88 | GAA (0.40) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL4727651 | 0.86 | MARS1 (0.43) | ALPLCNR1CNR2KCNH2NR1I2 | |
| SCHEMBL4729634 | 0.83 | KDM4E (0.40) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL4731047 | 0.82 | MAPT (0.43) | MAPTNPC1POLBTSHRRAB9A | |
| SCHEMBL2171236 | 0.80 | L3MBTL1 (0.38) | MAPTNPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |