Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725654 | 0.84 | FAAH (0.49) | FAAHCYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14292059 | 0.83 | EGFR (0.52) | AOC3FAAHCLK4DYRK1AMEN1 | |
| SCHEMBL14292785 | 0.82 | EGFR (0.56) | AOC3FAAHMAPK1MAPT | |
| SCHEMBL14292475 | 0.82 | FAAH (0.47) | AOC3FAAHCLK4CYP2D6CYP1A2 | |
| SCHEMBL4779907 | 0.82 | EGFR (0.65) | AOC3FAAHMEN1LMNAKMT2A | |
| SCHEMBL4780125 | 0.82 | FAAH (0.51) | FAAHCYP2D6 | |
| SCHEMBL4726563 | 0.81 | MEN1 (0.56) | AOC3FAAHCLK4DYRK1AMEN1 | |
| SCHEMBL4728074 | 0.81 | EGFR (0.58) | AOC3FAAHMEN1LMNAKMT2A | |
| SCHEMBL14292081 | 0.81 | CYP2D6 (0.61) | AOC3FAAHL3MBTL1CYP2D6MAPK1 | |
| SCHEMBL4726854 | 0.81 | CYP2D6 (0.61) | AOC3FAAHL3MBTL1CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |