Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725654 | 0.85 | FAAH (0.49) | FAAHCYP2D6 | |
| SCHEMBL4727781 | 0.84 | FAAH (0.56) | FAAH | |
| SCHEMBL4847869 | 0.84 | CYP2D6 (0.61) | FAAHCYP2D6 | |
| SCHEMBL4726854 | 0.84 | CYP2D6 (0.61) | FAAHCYP2D6 | |
| SCHEMBL14292081 | 0.84 | CYP2D6 (0.61) | FAAHCYP2D6 | |
| SCHEMBL4838019 | 0.82 | STK17A (0.49) | FAAH | |
| SCHEMBL4727972 | 0.82 | AOC3 (0.54) | FAAHCYP2D6 | |
| SCHEMBL14292048 | 0.81 | AURKA (0.49) | FAAH | |
| SCHEMBL14292784 | 0.81 | CDK2 (0.48) | FAAHCCNT1 | |
| SCHEMBL14292468 | 0.80 | MAPK8 (0.51) | FAAHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |